Therapeutic effects of CTLA4Ig-overexpressing mesenchymal stem cell-derived extracellular vesicles in a mouse model of rheumatoid arthritis.

Stem Cell Res Ther · 2025 · PMC12261591 · PMID 40660327

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

did not reach statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

Despite these promising results, the difference in arthritis scores between the CT and C groups did not reach statistical significance ( p = 0.052).

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a decreasing trendno p-value reported

Although not statistically significant, the CT group exhibited a decreasing trend in Th1 and Th17 levels compared with the C group.

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