MyD88-mediated signaling in intestinal fibroblasts regulates macrophage antimicrobial defense and prevents dysbiosis in the gut.

Cell Rep · 2025 · PMC12262590 · PMID 40257864

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did not reach statistical significanceno p-value reported

A significant increase in the basal level of overall Arg1 mRNA and a decrease in Camp mRNA were also observed in the co-culture of BM monocytes with MyD88 KO fibroblasts when compared to MyD88 WT fibroblasts, while the decrease in the basal level of Nos2 did not reach statistical significance ( Figure 5C ).

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