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Non-linear association between dietary fiber intake and cognitive function mediated by vitamin E: a cross-sectional study in older adults.

Front Nutr · 2025 · PMC12263355 · PMID 40672427

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However, the mediation effect did not reach statistical significance in participants with depression or borderline diabetes, which is likely attributable to the limited sample size in these subgroups (depression: n = 225; borderline diabetes: n = 118). 4 Discussion Through analysis of data from 2,713 older adults aged ≥60 years in the NHANES 2011–2014 database, there appears to be J-shaped relationships between dietary fiber intake and both DSST and total cognitive scores, suggesting the existence of optimal intake ranges.

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