Population Pharmacokinetics and Exposure-Response Analysis of Benralizumab in Chinese Adults, Adolescents, and Pediatric Participants with Severe Eosinophilic Asthma.

Clin Pharmacokinet · 2025 · PMC12263781 · PMID 40551003

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showed a trendno p-value reported

The simulated Chinese adolescent population showed a trend for higher median exposure than in Chinese adults ( C max +16.8%, C avg +19.9%, C trough +24.7%) due to differences in body weight but with a large overlap of distribution between the two groups.

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