Chronic 17β-estradiol treatment improves negative valence, anhedonic profile, and social interactions in ovariectomized, middle-aged female rats.

Front Behav Neurosci · 2025 · PMC12263923 · PMID 40672384

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hedged sentences

0.0060

closest p · 0.1× alpha

0.0730

boldest claim

The sentences

highly significantp = 0.006actually significant

A Pearson correlation revealed a highly significant effect for VEH (r = −0.716, n = 13, p = 0.006) with no significant effect for E2.

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marginally significantp = 0.054so close (0.05 < p ≤ 0.1)

The correlation was marginally significant (r = 0.350, n = 31, p = 0.054) with a tendency for higher composite z-scores for MBT to correspond with longer latencies of rats to approach food in the center of the NSF ( Figure 5G ).

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approached significancep = 0.073so close (0.05 < p ≤ 0.1)

For the Pearson correlation comparing the FST immobility with the duration to initiate grooming on the SST, the effect approached significance (r = 0.350, n = 27, p = 0.073).

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