Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes.

The independent and moderating effects of AS and CBF on total hippocampal volume Cross-sectional analyses In baseline models, no statistically significant association was seen between Cf -PWV ( B = 0.04; 95% CI = −0.01, 0.07; p = 0.06) or CBF ( B = 0.01; 95% CI = −2.45 × 10 −3 , 0.02; p = 0.19) at Wave 3 and total hippocampal volume when examined independently or when mutually adjusted including an interaction term between Cf -PWV and CBF which also did not reach statistical significance ( B = 3.70 × 10 −3 ; 95% CI = −1.07 × 10 −3 , 8.47 × 10 −3 ; p = 0.09).

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