Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD.

Nature · 2025 · PMC12267058 · PMID 40533550

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nominally significantno p-value reported

We compared our DEG results to a partially overlapping smaller dataset ( n = 10–11 per diagnostic group) 26 and found moderate overlap in the number and direction of nominally significant DEGs with both our PTSD (61.4%) and MDD (72.7%) cohorts across cell types (Extended Data Fig. 3f,g ).

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