Longitudinal profiling of hormone receptor positive, HER2 negative metastatic breast cancer through droplet digital PCR-based circulating tumor DNA fragmentomics.

Transl Oncol · 2025 · PMC12268100 · PMID 40577963

Europe PMC DOI

hedged sentence

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

did not reach statistical significanceP = 0.077so close (0.05 < p ≤ 0.1)

ACTB short Q1vs Q2 was associated with worse PFS but did not reach statistical significance (HR 1.67, CI 0.95–2.93 P = 0.077) ( Fig. 2 , Table 3 ).

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