The AhR regulates IFN-induced immune checkpoints in lung cancer cells through HNRNPH1, an RNA-binding protein, and INCR1, a novel long non-coding RNA.

J Biol Chem · 2025 · PMC12268640 · PMID 40449595

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a significant trendno p-value reported

Therefore, extremely large changes in fold-increases should be interpreted as a significant trend in gene up-regulation and not an exact quantification of the degree of mRNA increase.

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