Synergistic effects of NF-κB1 and inflammatory pathway polymorphisms on hypertension and dyslipidemia susceptibility in type 2 diabetes.

Diabetol Metab Syndr · 2025 · PMC12269108 · PMID 40671147

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.1420

boldest claim

The sentences

approached significanceP = 0.055so close (0.05 < p ≤ 0.1)

Global haplotype distribution approached significance ( c 2 = 13.791, P = 0.055).

also in 8,237 other papers

borderline significanceP = 0.071so close (0.05 < p ≤ 0.1)

AG heterozygotes showed borderline significance in unadjusted analysis (OR = 0.486,95%CI 0.222–1.064;P = 0.071) that reached statistical significance after adjustment (adjusted OR = 0.278,95%CI 0.109–0.710;P = 0.007).

also in 7,017 other papers

a trend toward significanceP = 0.142not close (p > 0.1)

For TLR4 rs2149356, recessive model analysis indicated a trend toward significance for the GG genotype (52.7% in T2MH-DYS vs. 39.4% in T2MH; c 2 = 2.160,P = 0.142).

also in 3,729 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.