In general, most of the changes reported previously ( 21 ) were also observed in the current study, namely a highly significant reduction in levels of VLC-SLs and an increase in LC-SLs and sphinganine (d18:0-LCB).
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Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects.
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The sentences
S1 ) and showed a trend similar to the canonical ones.