Barely Significant
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Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3.

EBioMedicine · 2025 · PMC12270663 · PMID 40609154

Europe PMCDOI
1
hedged sentence
0.2000
closest p · 4.0× alpha
0.2000
boldest claim

The sentences

did not reach statistical significanceP = 0.2not close (p > 0.1)
In WT mice, although cagrilintide treatment led to significant weight loss, the changes in body composition compared to vehicle-treated mice did not reach statistical significance, with fat mass decreasing by 7% ( P = 0.2) and lean mass increasing by 5% ( P = 0.14. two-way ANOVA; Fig. 3 a and b).

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