Interleukin-6 in synovial fluid drives the conversion of DC2s to DC3s in inflammatory arthritis.

iScience · 2025 · PMC12270937 · PMID 40687784

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Regarding the priming of the specific CD4 T cell subsets, CD1c + CD14 + CD163 + DC3s in SF showed a trend toward reduced amounts of IL-4 + CD4 T cells and a significantly higher proportion of IFN γ + CD4 T cells ( Figure 2 D).

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