Effect of chorioamnionitis on necrotizing enterocolitis in preterm infants: a multicenter cohort study.

As previously reported in the literature, the association between chorioamnionitis (CAM) and necrotizing enterocolitis (NEC) may not be significant in preterm infants with lower birth weights or smaller gestational ages, which is consistent with the results of our stratified analysis by gestational age ( 14 ).

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In a multifactorial logistic regression model, after correcting for covariates such as sex, gestational age, and birth weight, CAM was associated with NEC, but this association did not reach statistical significance (aOR = 1.35, 95% CI 0.68–2.69).

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