Effects of a kappa opioid receptor antagonist on delayed postoperative pain recovery in a novel mouse sleep disorder model.

Front Pain Res (Lausanne) · 2025 · PMC12271097 · PMID 40687342

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did not reach statistical significanceno p-value reported

Additionally, although we observed a trend toward REM sleep reduction in the PAWW group, this difference did not reach statistical significance.

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a decreasing trendno p-value reported

EEG recordings confirmed a significant reduction in total sleep time during the light phase, with a decreasing trend also observed during the dark phase.

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