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Circulating adiponectin levels in systemic sclerosis: A meta-analysis and bidirectional Mendelian randomization study.

J Scleroderma Relat Disord · 2025 · PMC12271137 · PMID 40686938

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However, their results did not reach statistical significance in Europeans when ethnicity-stratified analyses were performed. 14 , 15 Since then, several studies in Europeans have been conducted, with two reporting lower serum levels of adiponectin in SSc patients compared to controls, 16 , 17 while the others found no significant difference. 18 - 20 Mendelia

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