Chronic benzodiazepine treatment triggers gephyrin scaffold destabilization and GABA<sub>A</sub>R subsynaptic reorganization.

Consistent with our DNA-PAINT analysis ( Figure 2 ), this occurred with a near-significant decrease in synaptic full-length gephyrin ( Figure 4B ; Veh = 100.0 ± 7.01%, DZP = 75.16 ± 9.64%; p = 0.0559).

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