CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo.

After normalizing cleared area to spheroid starting size to account for differences in spheroid viability due to loss of CAMKKβ (as recommended 39 ), we identified a strong trend toward decreased invasive potential in OVCAR8 CAMKK2 KO spheroids but observed no effect in HeyA8 CAMKK2 KO spheroids (Fig. 3 B).

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