Appendicitis burden trends in European region In the Europe region, from 1990 to 2019, the AAPC of the ASIR showed a positive trend, with values of 0.50% (95% CI: 0.45%–0.54%) for both sexes combined, 0.49% (95% CI: 0.44%–0.54%) for females, and 0.50% (95% CI: 0.46%–0.54%) for males ( Figure 5 and Table 2 ).
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Appendicitis burden, trends, and inequalities in Europe, 1990-2019: a population-based study.
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Between 1990 and 2019, both the incidence and ASIR of appendicitis in males and females in the European region showed an increasing trend, with females consistently slightly higher than males ( Figure 1 ).
The AAPC of ASMR showed a negative trend: -3.02% (95% CI: -3.23% to -2.80%) for both sexes, -3.30% (95% CI: -3.53% to -3.08%) for females, and -2.86% (95% CI: -3.16% to -2.56%) for males.