Although no statistically significant differences in EC cell counts were observed in neither loperamide treatment nor GKB7 group, an increasing trend of cell number was noted in the GKB7-treated group ( Fig. 2 H). 3.2 Enhancement of bowel functions of Clostridium butyricum GKB7 Constipation was induced in rats by administering loperamide to reduce bowel motility.
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Health-promoting effects of <i>Clostridium butyricum</i> GKB7 on the gastrointestinal tract in murine models.
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Notably, although the increase in EC cells did not reach statistical significance, the upward trend implies that strain GKB7 may contribute to the normalization of intestinal permeability and gastrointestinal motility ( Fig. 2 G).