Barely Significant
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Health-promoting effects of <i>Clostridium butyricum</i> GKB7 on the gastrointestinal tract in murine models.

Biochem Biophys Rep · 2025 · PMC12275026 · PMID 40688492

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an increasing trendno p-value reported
Although no statistically significant differences in EC cell counts were observed in neither loperamide treatment nor GKB7 group, an increasing trend of cell number was noted in the GKB7-treated group ( Fig. 2 H). 3.2 Enhancement of bowel functions of Clostridium butyricum GKB7 Constipation was induced in rats by administering loperamide to reduce bowel motility.

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Notably, although the increase in EC cells did not reach statistical significance, the upward trend implies that strain GKB7 may contribute to the normalization of intestinal permeability and gastrointestinal motility ( Fig. 2 G).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.