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Perioperative use of esketamine for the prevention of postpartum depression after cesarean section: a meta-analysis.

BMC Pregnancy Childbirth · 2025 · PMC12275314 · PMID 40684106

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This study found that intravenous injection during the operation combined with continuous infusion through an analgesic pump for 48 h after the operation (Group C) can reduce the incidence of PPD one week after childbirth by 51%, while single administration during the operation alone (Group A) or infusion only through the postoperative analgesic pump (Group B) did not reach statistical significance.

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