a trend toward significancep = 0.06
For negative symptoms, the improvement showed a trend toward significance with an MD of −1.35 (95% CI: −2.74 to 0.04; I 2 = 71%; p = 0.06; τ 2 = 3.27) (Figure 3 ). 3.4 Subgroup Analysis We conducted a subgroup analysis of different doses of raloxifene, duration, and menopausal status in women.