Deciphering per- and polyfluoroalkyl substances mode of action: comparative gene expression analysis in human liver spheroids.

Toxicol Sci · 2025 · PMC12279298 · PMID 40037795

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did not reach statistical significanceno p-value reported

PPARα’s activity was predicted to be upregulated after exposure to PFOA, PFBS, and the PPAR agonists, whereas PFOS and PFDS upregulation of PPARα activity did not reach statistical significance.

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