There is a clear trend in the data showing that a reduction in the proportional contribution of healthcare costs is accompanied by an increase in the contribution of indirect costs, as severity progresses (Figure 2 ).
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Major Cost Drivers in Assessing the Economic Burden of Alzheimer's Disease: A Structured, Rapid Review.
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This result remained highly significant after adjusting for age, sex, race, education, marital status, residential region and comorbidities (<0.015).