Early-life anthropometry and colorectal cancer risk in adulthood: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis of prospective studies.

The two available MR studies reported RRs >1 for genetically predicted adiposity at age 10 and CRC risk, although associations did not reach statistical significance. 63 , 79 One MR study, stratified by tumour subsite, also reported RRs >1 for colon and rectal cancer risk. 79 No MR studies were identified for adolescent height. 3.4 Young adult anthropometry For young adult BMI, the linear meta‐analysis included 20,365 CRC cases from 16 studies. 54

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