Short-Chain Polychlorinated Alkanes Exposure and Risk of Thyroid Cancer in a Population-Based Case-Control Study.

Although overall PCAs-C 10–13 levels were similar across the sexes, a slight trend toward higher serum levels was observed in females.

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For males, RCS analysis showed a trend similar to that observed in the logistic regression, indicating nonsignificant reductions in thyroid cancer risk with PCAs-C 10–13 exposure.

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Similar to the WQS findings, BKMR analysis showed a nonsignificant trend toward reduced thyroid cancer risk when all PCAs-C 10–13 were collectively considered at specific percentiles (ranging from 25th to 75th) compared to their median values, both in the case and control groups and sex-specific subgroups ( Figure A–C).

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