Direct pharmacological AMPK activation inhibits mucosal SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy flux and the type I IFN response.

J Virol · 2025 · PMC12282067 · PMID 40503889

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showed a trendno p-value reported

The concentrations of MK-8722 tested had no negative impact on the expression of activation markers and even showed a trend toward increased activation with MK-8722 treatment.

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