High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection.

J Virol · 2025 · PMC12282198 · PMID 40503880

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4I ), the high-dose AAV-HBV mice that failed to clear HBV once again showed a trend toward higher percentages of PD-1-expressing CD8+ T cells in the liver than low-dose mice.

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