Combination of PSMA targeting alpha-emitting radioligand [²¹²Pb]Pb-AB001 with BET bromodomain inhibitors in in vitro prostate cancer models.

[ 212 Pb]Pb-AB001 exposure showed a trend toward an activity- and time-dependent increase in DNA damage, assessed via phosphorylated γH2AX, although this was not significant due to high variability between experiments (Fig. 4 b).

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