Barely Significant
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Longitudinal behavioral and neuropsychiatric changes and their MRI correlates in predementia <i>C9orf72</i> and <i>GRN</i> mutation carriers.

J Alzheimers Dis · 2025 · PMC12284341 · PMID 40534487

Europe PMCDOI
2
hedged sentences
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)
Longitudinal mixed effects model of NPS change rates (NPS analysis) NPI-Q: Total Scores : Longitudinal rates of change in the NPI-Q total scores were not significantly different among C9orf72+ , GRN + and non-carriers, although GRN + showed a trend towards an overall increase in the total score (p = 0.06) ( Figure 1A ).

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an overall trendno p-value reported
GRN + showed an overall trend towards increases in all four subsyndromes, which explained the overall trend of increase in the NPI-Q total score.

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