Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes.

Acta Neuropathol Commun · 2025 · PMC12285028 · PMID 40696405

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Similarly, ATRT-MYC tumors showed a trend towards the least amount of actively expressed loci again both for LINEs (median ± SD: MYC 21,778 ± 6,047; SHH 22,316 ± 3,170; TYR 22,855 ± 384) and LTR elements (median ± SD: MYC 12,821 ± 2,229; SHH 14,113 ± 1,048; TYR 13,636 ± 689) (Fig. 1 e).

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