Temporal TCR dynamics and epitope diversity mark recovery in severe COVID-19 patients.

Front Immunol · 2025 · PMC12286809 · PMID 40709175

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a decreasing trendno p-value reported

Likewise, other pro-inflammatory cytokines, including IL-6, IP-10, and IL-1a, exhibited a decreasing trend from T1 to T3, where the decrease from T2 to T3 was found to be significant ( Figures 5C–E ).

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did not reach statistical significanceno p-value reported

While individual-level correlations at this time-point did not reach statistical significance, this pattern reinforces the longitudinal shift from inflammation to immune recovery.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.