Clostridioides difficile co-infection worsens prognosis in inflammatory bowel disease in patients with cytomegalovirus colitis.

Int J Colorectal Dis · 2025 · PMC12287193 · PMID 40699310

Europe PMC DOI

hedged sentences

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

did not reach statistical significancep = 0.095so close (0.05 < p ≤ 0.1)

Similarly, another study reported 1-year colectomy-free survival rates of 30% in the co-infection group and 57.1% in the CMV monoinfection group—a difference that did not reach statistical significance ( p = 0.095) [ 1 ], further supporting the notion that co-infection does not significantly increase colectomy risk.

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an increasing trendno p-value reported

Early research has demonstrated that the prevalence of CDI among hospitalized patients with UC ranged from 3.7 to 4.2% [ 10 , 11 ], while more recent studies have shown an increasing trend, with rates ranging from 6 to 9% [ 12 , 13 ].

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