The global, regional, and national burden trends of dengue among adults aged 20-49 from 1990 to 2021.

Sci Rep · 2025 · PMC12287444 · PMID 40702040

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did not reach statistical significanceno p-value reported

Before 2012, the ASMR in this age group rose significantly; although it subsequently declined, it did not reach statistical significance.

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an increasing trendno p-value reported

From a temporal trend perspective, the ASIR (EAPC = −1.15, 95% CI: −1.54, −0.76) and ASPR (EAPC = −1.16, 95% CI: −1.56, −0.77) in the low SDI region exhibited a downtrend, while the ASMR (EAPC = 1.21, 95% CI: 0.77, 1.65) exhibited an increasing trend, and the ASDR (EAPC = 0.22, 95% CI: −0.07, 0.50) exhibited no remarkable change.

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