Pentose phosphate pathway inhibition metabolically reprograms CD8+ T cells and disrupts CNS autoimmunity.

JCI Insight · 2025 · PMC12288970 · PMID 40493395

Europe PMC DOI

hedged sentence

0.0556

closest p · 1.1× alpha

0.0556

boldest claim

The sentences

did not reach statistical significanceP = 0.0556so close (0.05 < p ≤ 0.1)

Furthermore, we observed a trend toward increased PPP engagement in PPMS, though these results did not reach statistical significance (CON versus PPMS, n = 3, P = 0.0556).

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