Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer's disease: a systematic review and meta-analysis.

Front Pharmacol · 2025 · PMC12289687 · PMID 40717971

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.1200

boldest claim

The sentences

borderline significanceP = 0.054so close (0.05 < p ≤ 0.1)

This observation was statistically confirmed through Egger’s test for escape latency, target quadrant occupancy, and MDA (all P < 0.05); however, SOD showed borderline significance ( P = 0.054).

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failed to reach statistical significanceP = 0.12not close (p > 0.1)

However, this reduction failed to reach statistical significance ( P = 0.12) ( Figure 6 ).

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