Barely Significant
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Combined exposure to three heavy metals and the risk of age-related macular degeneration in the Korean population.

Sci Rep · 2025 · PMC12290029 · PMID 40707687

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a positive trendno p-value reported
Figure 2 C shows the overall effect of the combined heavy metal mixture on AMD, revealing a positive trend across increasing exposure quantiles.

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a clear trendno p-value reported
Pb and AMD revealed a positive linear association, Cd exhibited a U-shaped relationship, and the exposure-response function for Hg did not exhibit a clear trend.

also in 19,460 other papers

marginally significantno p-value reported
The overall mixed effect of heavy metals on AMD demonstrated a dose-response relationship, but the effect was marginally significant among non-smokers.

also in 26,082 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.