Unraveling the Genetic Link Between Endocrine Hormones and Psychiatric Disorders: An Atlas of Genetic Correlations.

When examining the genetic overlap between thyroid hormones and sex hormones, we observed suggestive, nominally significant positive genetic correlations between testosterone and both FT3 ( p = 3.00 × 10 −3 ) and FT4 ( p = 7.90 × 10 −3 ), as well as a Bonferroni-significant positive genetic correlation between FT4 and SHBG ( p = 2.00 × 10 −4 ); we additionally observed a suggestive negative genetic correlation between testosterone and TSH ( p = 4.50 × 10 −3 ). 3.3.

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