Mechanisms of Cisplatin-Induced Acute Kidney Injury: The Role of NRF2 in Mitochondrial Dysfunction and Metabolic Reprogramming.

Antioxidants (Basel) · 2025 · PMC12291884 · PMID 40722880

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In a CKD model with repeated low-dose cisplatin injections, KO mice showed a trend toward increased Scr and BUN levels, but differences were not significant, likely due to compensatory renal mechanisms.

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