Barely Significant
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The Effect of Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, on Vancomycin-Induced Nephrotoxicity in Rats.

Biomedicines · 2025 · PMC12292332 · PMID 40722655

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a decreasing trendno p-value reported
Although the addition of DAPA to the VA group (the DAPA+VA group) resulted in a decreasing trend in MDA levels compared to the VA group, this difference was not statistically significant ( Figure 2 A).

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In the DAPA+VA group, these scores were lower than those in the VA group; although the differences did not reach statistical significance, DAPA treatment was associated with a trend toward reduction in the VA-induced increases in TNF-α (the most pronounced trend), IL-1β, and IL-6.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.