Genetic Factors Associated with Intraocular Inflammation After Brolucizumab Administration in Patients with Exudative Age-Related Macular Degeneration.

Genes (Basel) · 2025 · PMC12294146 · PMID 40725453

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

did not reach statistical significancep = 0.055so close (0.05 < p ≤ 0.1)

The T allele of the cholesteryl ester transfer protein ( CETP ) rs3764261 was significantly protective against IOI development ( p = 0.038, chi-square test), although the incidence of IOI did not reach statistical significance ( p = 0.055) between the switching group and the treatment-naïve group.

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