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Adult-Onset Deletion of CDKL5 in Forebrain Glutamatergic Neurons Impairs Synaptic Integrity and Behavior in Mice.

Int J Mol Sci · 2025 · PMC12294185 · PMID 40724873

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Although this reduction persisted up to 12 weeks, it did not reach statistical significance ( Figure 1 E), suggesting that Cdkl5 deficiency may modestly impair somatic growth or influence food intake.

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