Repeatome Analysis of Plasma Circulating DNA in Patients with Cardiovascular Disease: Variation with Cell-Free DNA Integrity/Length and Clinical Parameters.

Int J Mol Sci · 2025 · PMC12294208 · PMID 40724907

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp -value < 0.001actually significant

Concerning the other repeat families, highly significant ( p -value < 0.001) correlations were found in dinucleosomal cfDNA for L1HS with troponin and for ALR with Nt-proBNP.

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weakly significantno p-value reported

However, none of the considered cfDNA parameters (Alu, ALR and L1HS relative abundance in dinucleosomal cfDNA) correlated with other comorbidities, while only ALR relative abundance showed a weakly significant correlation with an inflammatory parameter (NLR).

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