Reassessing the Use of Membranes in Peri-Implantitis Surgery: A Systematic Review and Meta-Analysis of In Vivo Studies.

J Funct Biomater · 2025 · PMC12295663 · PMID 40710476

Europe PMC DOI

hedged sentences

0.0390

closest p · 0.8× alpha

0.5500

boldest claim

The sentences

marginal significancep = 0.039actually significant

The PPD analysis revealed largely symmetrical funnel plots with no evidence of asymmetry in the BG group ( p = 0.489) and only marginal significance in the GBR group ( p = 0.039), suggesting minimal publication bias.

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failed to reach statistical significancep = 0.55not close (p > 0.1)

Despite the greater mean gain in the membrane group, the test for subgroup differences failed to reach statistical significance ( p = 0.55), indicating no clear therapeutic advantage of membrane application over BG alone.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.