Inverse effects of lymph node count on oncological outcomes in rectal cancer based on lymph node positivity status post-neoadjuvant CRT: a large-volume Chinese center experience.

Int J Colorectal Dis · 2025 · PMC12296959 · PMID 40715794

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0680

boldest claim

The sentences

a significant trendP = 0.010actually significant

However, a significant trend of higher LN count and higher likelihood of liver metastases was observed ( P = 0.010).

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marginally significantP = 0.068so close (0.05 < p ≤ 0.1)

The RCS analysis revealed a link between a higher LN count and a better DFS ( P = 0.007), and there was a marginally significant trend suggesting a potential link between a higher LN count and an improved OS ( P = 0.068).

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marginal significanceno p-value reported

In the multivariable analysis, high rectal cancer was not confirmed as an independent factor for higher LN retrieval due to only marginal significance, likely attributable to the smaller sample size ( n = 82) compared with mid-rectal cancer ( n = 789) and low rectal cancer ( n = 612).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.