Indeed, both ITT and PP analyses showed a trend of reduced intracranial bleeding for DOACs initiators than warfarin initiators (HR = 0.78 (0.45, 1.35) and HR = 0.38 (0.13, 1.12)), but the treatment effects were not statistically different.
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Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients with Atrial Fibrillation and Cancer: A Target Trial Emulation from SEER-Medicare Database.
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