Barely Significant
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Targeting Langerhans cells via skin delivery of HIV Envelope enhances the antibody response to vaccination.

NPJ Vaccines · 2025 · PMC12297313 · PMID 40715153

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hedged sentence
0.0510
closest p · 1.0× alpha
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boldest claim

The sentences

approached significanceP = 0.051so close (0.05 < p ≤ 0.1)
administration of αLang.Env in Xcr1 DTA mice induced Env IgG titers at day 27 that approached significance ( P = 0.051) compared to PBS controls, with responses confirmed when analyzing the overall Env IgG kinetics (Supplementary Fig.

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