Comparative Study: Biguanide-, Sulfonamide-, and Natural Agent-Based Interventions in an In Vivo Experimental Diabetes Model.

Medicina (Kaunas) · 2025 · PMC12297955 · PMID 40731781

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a positive trendno p-value reported

Across all groups, Pearson’s correlation analysis revealed no statistically significant associations between dose and glycemic response, though a positive trend was noted for metformin (r = 0.805) and the S + sage combination (r = 0.68).

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did not reach statistical significanceno p-value reported

Although groups L3 and L4 (sulphonamide and metformin monotherapies) showed blood reductions in blood glucose levels, they did not reach statistical significance when compared to the untreated diabetic group (L2) (L2 vs.

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