Germinated Spores of the Probiotic Bacterium <i>Bacillus coagulans</i> JBI-YZ6.3 Support Dynamic Changes in Intestinal Epithelial Communication and Resilience to Mechanical Wounding.

In contrast, both the metabolite and the cell wall fractions triggered mild decreases in IP-10 levels after 2 h of treatment at the two higher doses, with the highest dose of the metabolite fraction showing a statistical trend and the middle dose of the cell wall fraction reaching statistical significance ( Figure 5 A).

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In the absence of inflammation, the metabolite fraction supported wound healing better than the cell wall fraction but did not reach statistical significance.

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Under normal conditions, only the metabolite fraction contributed to the MIP-1α reduction at the middle dose, whereas the cell wall fraction triggered highly significant increased MIP-1α levels at the two higher doses ( Figure 5 C).

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