Barely Significant
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Multivalent COBRA Hemagglutinin and Neuraminidase Influenza Vaccines Adjuvanted with TLR9 Agonist CpG 1018.

Vaccines (Basel) · 2025 · PMC12298839 · PMID 40733639

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showed a trendno p-value reported
Pre-immune mice that were vaccinated intranasally with COBRA HA/NA vaccines mixed with CpG 1018 showed a trend to higher IgG titers in the BALF against both HA and NA proteins compared to mice vaccinated with COBRA vaccines without adjuvant.

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